Lesch-Nyhan Syndrome is caused due to the deficiency of.....

Options :
  1. Hypoxanthine guanine phosphoribosyl transferase
  2. Isocitrate dehydrogenase
  3. Xanthine oxidoreductase
  4. adenine phosphoribosyltransferase
Answer and Explanation :-

Answer: Option 1


HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. HGPRT plays a central role in the generation of purine nucleotides through the purine salvage pathway. Lesch-Nyhan syndrome is due to HPRT mutations resulting in extremely ineffective enzyme activity.

How do you rate this queston?  Very Easy  Easy  Average  Above Average  Tough

Previous Question : Male amphibians have a rudimentary ovary which is also known as.....

Next Question : Amino acids are amphiprotic molecules because of the presence of ......

Click here for online test on Biochemistry


 (Getemail alerts when others member replies)

Success is not final, failure is not fatal: it is the courage to continue that counts.
-Winston Churchill