Lesch-Nyhan Syndrome is caused due to the deficiency of.....

Options :
  1. Hypoxanthine guanine phosphoribosyl transferase
  2. Isocitrate dehydrogenase
  3. Xanthine oxidoreductase
  4. adenine phosphoribosyltransferase
Answer and Explanation :-

Answer: Option 1

Explanation:

HGPRT is a transferase that catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate. HGPRT plays a central role in the generation of purine nucleotides through the purine salvage pathway. Lesch-Nyhan syndrome is due to HPRT mutations resulting in extremely ineffective enzyme activity.

How do you rate this queston?  Very Easy  Easy  Average  Above Average  Tough

Previous Question : Male amphibians have a rudimentary ovary which is also known as.....

Next Question : Amino acids are amphiprotic molecules because of the presence of ......

Click here for online test on Biochemistry

Responses


 (Getemail alerts when others member replies)







If your failure is not a lesson, it's indeed a failure.
-Ogwo David Emenike The Fortune in Failing: Decoding the Message of Failure